Translational Research Assignment Help
(Nursing and Health Sciences Research Guide), find a database, journal, or other collection of resources that focuses on translational research. Select a population health problem or issue of interest from the available studies. What type of translational research is used for the study? Provide a rationale as to why this is the best type of translational research is best for the study, and explain why translational research is the most appropriate approach for this problem or population.
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Select a population health problem or issue of interest from the available studies.
The health problem discussed in the present report is “lupus”, which is a systemic autoimmune disease. This is a condition in which inflammation by lupus dance to modulate the immune system of body to attack own tissues and organs including skin, kidney, blood cells, heart, and lungs. In the present scenario this autoimmune disorder have no cure, however there are available treatments that can only control the symptoms.
What type of translational research is used for the study?
According to Zhang (2018), there exist a big question regarding the therapeutic measures to cure lupus, as some treatment work well for certain patients and not others. The translational research used mainly aims to address of objectives like (i) identification of suitable biomarkers to design noble therapy, and (ii) development of non-invasive strategies for early detection of lupus. Thus undertaken research work aims to establish method in which samples of renal tissue and non-lesion skins (endothelial cells) will be collected from patient before and after the treatment (Labonte, 2018). The RNA sequences will then be tested to obtain a patent with reference to race, disease onset, and ethnicity of patient.
Provide a rationale as to why this is the best type of translational research is best for the study,
This translational research is best of its type because it includes more than 300 patients for collection of samples. For lupus problem, the heterogeneous condition, systemic autoimmunity, and chronicity is not properly known. However it is known that the incidence of this disorder as well as its prevalence are highly affected by race and ethnicity (Labonte, 2018).
and explain why translational research is the most appropriate approach for this problem or population.
Translational research in this perspective is the most appropriate approach because it applies the knowledge of basic science with objective to find progression in treatment of lupus complication. The mentioned research work is a continuous evaluation of data directly from patient (clinical settings), and provides confirmation with reference to new drug targets as well as therapeutic efficiencies of existing treatment. The research work also provides refinement of data in conjunction to the variation in immune tolerance among different race and ethnicity (Crow, 2015). Such work involves multidisciplinary professionals and thus probability of achieving clinical efficiency increases to a significant level.
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