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BE6005 Biochemical Pathology Essay Assignment Help

How successful are nutritional supplements in reducing disease attributed to oxidant stress?

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Introduction

The primary purpose of the paper is to discuss the role of nutritional supplement in reducing the adverse impact of the disease related to oxidant stress. Oxidative stress is necessarily used for creating an imbalance between the ability of the body to detoxify or counteract with harmful effects and the production of free radicles by antioxidants. The nutritional supplementation help in optimizing the patient wellbeing by lowering the oxidative stress. A nutritional supplement is chosen, which is useful for treating the disease caused due to oxidant stress. The pros and cons of the nutritional supplement and also the strategy of reducing oxidative stress will also be provided in this context. Moreover, the role of nutritional supplement in reducing the diseases of human will also further briefly discussed in this paper.

Main context

Oxidative stress and the disease related to it

Oxidative stress generally occurs due to the disproportion of antioxidants and oxidants in the body of a human being. It plays an essential role in creating several pathophysiological conditions in the human body. It can instigate cell damage as well as tissue damage using two factors such as apoptosis and putrefaction (Johnston-Carey, Pomatto and Davies, 2016). Oxidative stress is generally developed by the contribution of free radicals that create illness in people. Research has shown that oxidative stress is taken up by froth cells and macrophages. Many researchers suggested that free radicals cause auxiliary harm to the tissue and create infection at the initiation of the regulatory proteins (Shaw et al., 2016). Thus several numbers of the disease have been generated by auxiliary stress such as malignancy, cardiovascular illness, Alzheimer's ailment, atherosclerosis, diabetes, rheumatoid joint pains, immune system problem, kidney ailments and AIDS. All these diseases create irritation and infection on the human body.

Nutritional supplement suggested for treating the disease

The nutritional supplement that has been suggested for treating the disease occurring due to oxidative stress is the ROS (Reactive Oxygen Species) potent antioxidant. This nutritional supplement is manifested in the human cells in the portion that is affected by detoxifying compounds and free radical exogenous (Bellant et al., 2018). From various research, it is noted that cancer prevention agents that structure the human body are considered as the necessary barrier of this nutritional supplement. The nutritional supplement when it reacts with the body converts into a glutathione, catalase and dismutase peroxidase. After transferring into peroxidase, it reduces the intruding as well as spreading of the disease in the human body. By this way, the nutritional supplement helps in treating the disease caused by oxidative stress.

Pros and cons of the nutritional supplement

Pros of the nutritional supplement

The nutritional supplement reduces the permanent state of the disease by supplying appropriate peroxides and radicals which is necessary for the human body (Bellant et al., 2018)
It increases the nutrition level of the individual by supplying the correct amount of glucose in the body

Cons of the nutritional supplement

The nutritional supplement if use overdose then it can increase the fat and lipid level of people suffering from oxidative stress
It can increase the obesity rate of people if it is used in excessive amount (Conti et al., 2016)

Strategies for reducing oxidative stress

It needs to be understood that higher levels of reactive oxygen species (ROS) are supposed to execute the vital role for diverse chronic age regarding diseases and ageing. Moreover, it needs to be understood that the invertebrate, as well as the vertebrate modes, must be separated because the collected data along with the results remain disparate when the role of antioxidants is estimated on longevity. Also, the addition of more Superoxide dismutase (SOD), as well as the catalysts enzymes within the genetic experiments, shows longer lifespan for model organisms and it indicates that the catalytic antioxidants retain the ability to enhance the life span (Li et al., 2015).

Various researches and practices have shown that other substances within the vegetables and fruits along with the inhibitors of angiogenesis can effectively contribute towards the enhancement of better cardiovascular health and it also helps in decreasing the cancer incidence within people who consume a higher amount of fruits and different type of vegetables. It also needs to be understood that the effective use of synthetic antioxidants is not considered as the alternative for the regular consumption of different types of fruits as well as vegetables. One of the alternative ways for enhancing the endogenous level of antioxidants can be the oxidative stress, which is based on the concept of the hormesis (Manna and Jain, 2015).

Role of nutritional supplements in reducing human diseases

There are several nutritional antioxidants which play a crucial role in the reduction of various cardiovascular and other human diseases. Anthocyanin is an antioxidant which shows alleviated Astrogliosis as well as preserved neuromuscular junctions with the muscle functions in Amyotrophic lateral sclerosis (ALS) (Cuhls et al., 2017). Lipoic acid helps in protecting neurons against the OS-induced mitochondrial dysfunctions. Lycopene helps in facilitating and improving clinical asthma results by defeating the airway inflammation. It also helps in reducing the low-density lipoprotein (LDL) oxidation within the blood.

These antioxidants generate a significant amount of impact on human diseases; therefore, their primary sources should be known to human beings. On the other hand, the Polyphenols comes from various fruits and vegetables, coffee and tea and these works as anti-cancer activity against the lungs, breast, colon and tongue. The use of vitamin C is considered as vital for reducing the airway inflammation as well as for exercise-induced bronchoconstriction (Rani et al., 2016). Moreover, the intake of vital A and C are considered to be inversely linked within the occurrence of asthma. The use of vitamin D is for improving respiratory muscle operations as well as exercise capabilities. It also helps in enhancing the density of bones and reduces the risks for hip along with other fractures.

Conclusion

The paper evaluated the desired impact of the various nutritional supplements that helps in reducing disease attributed to oxidant stress. It also reflected the various Nutritional supplements that are suggested for reducing various diseases. It becomes essential for people to evaluate the importance of the pros and cons of the diseases and the role of antioxidants, which can help prevent them from these diseases. There are specific crucial strategies reflected throughout the paper, which can be effectively utilized in order to reduce the oxidant stress, which prevails in human beings. Moreover, the paper also reflects the role of h nutritional antioxidants for the reduction of various diseases.

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