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HCAS 143 Human Disease and Drug Pharmacology

Drug discovery as per the course HCAS 143 Human Disease and Drug Pharmacology, practice has escaped from the complexity of the formerly used phenotypic screening in animals to concentrate on assessing drug effects on isolated protein targets in looking for drugs that exclusively and potently hit one of the target which is selected, thought to be critical for a given disease, while not hitting at all any other target to avoid the occurrence of side-effects. However, as per the course HCAS 143 Human Disease and Drug Pharmacology, reality does not conform to these expectations, and, actually, this approach has been concurrent with increased attrition, precisely because of lack of efficacy and safety. 

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