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CHEM 5753 Principles of Biochemistry

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Brief overview of the course:

This CHEM 5753 Principles of Biochemistry course is an advanced undergraduate course and a required course for postgraduate students specializing in biochemistry. This course is a continuation of the material presented in the CHEM 3653 Introduction to Biochemistry. Therefore, an introductory course is a must. The course will build on the students' general experience in biochemistry and will address broader topics in the application of metabolic and genetic information pathways. Therefore, topics such as energy production and use, structure and catalysis, control, DNA replication and gene expression will generally be emphasized.

The principle of biochemistry combines the introduction of macromolecular structure and the biochemical method of cell function. Topics relating to protein function will include enzyme kinetics, characterization of major metabolic pathways and their interactions with tight regulatory networks, and manipulation of enzymes and pathways through mutations or drugs. Research from simple cells (red blood cells) to more complex tissues (muscles and liver) will be used as a basis for discussing the progress of metabolic complexity. Students will also develop problem-solving and analytical skills that are more applicable to life sciences.

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